This letter reports on a method for producing on demand calibrated bubbles in a non-chemically controlled solution using localized micro-electrolysis and ultrasound. Implementing a feedback loop in the process leads to a point source of stable mono-dispersed microbubbles. This approach overcomes the inertial constraints encountered in microfluidics with the possibility to produce from a single to an array of calibrated bubbles. Moreover, this method avoids the use of additional surfactant that may modify the composition of the host fluid. It impacts across a broad range of scientific domains from bioengineering, sensing to environment.
Achaoui, Y., Metwally, K., Fouan, D., Hammadi, Z., Morin, R., Debieu, E., … Mensah, S. (2017). Tunable microbubble generator using electrolysis and ultrasound. AIP Advances, 7(1). https://doi.org/10.1063/1.4973720