Effect of Neuroprotective Flavonoids of Agrimonia eupatoria on Glutamate-Induced Oxidative Injury to HT22 Hippocampal Cells

47Citations
Citations of this article
24Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

A methanolic extract of Agrimonia eupatoria (Rosaceae) significantly attenuated glutamate-induced oxidative stress in HT22 hippocampal cells. A new flavonoid, characterized as kaempferol 3-O-β-D-(2″-O-acetyl- 6″-(E)-p-coumaroyl)-glucopyranoside (2″-acetyltiliroside (1), was isolated from the methanolic extract of A. eupatoria stems together with nine known flavonoids. Compounds 4, 7, 8 and 9 all showed a neuroprotective effect on glutamate-induced toxicity in HT22 cells.

Cite

CITATION STYLE

APA

Lee, K. Y., Hwang, L., Jeong, E. J., Kim, S. H., Kim, Y. C., & Sung, S. H. (2010). Effect of Neuroprotective Flavonoids of Agrimonia eupatoria on Glutamate-Induced Oxidative Injury to HT22 Hippocampal Cells. Bioscience, Biotechnology and Biochemistry, 74(8), 1704–1706. https://doi.org/10.1271/bbb.100200

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free