Managing breast cancer risk

Abstract

Evaluation of risk -- Overview of clinical risk assessment -- Familial and genetic risk -- Endocrine risk factors -- Benign breast disease and breast cancer risk -- Lifestyle, environmental factors, and breast cancer risk -- Breast cancer risk in the context of overall health -- Risk management strategies -- Surveillance -- Outcome of routine surveillance of the high-risk woman -- Newer imaging approaches to the high-risk woman -- Role of breast epithelial sampling techniques in high-risk women -- Chemoprevention -- Biologic basis for breast cancer risk reduction with pharmacologic agents -- Tamoxifen for chemoprevention -- SERMs other than tamoxifen for chemoprevention -- Aromatase inhibitors for chemoprevention -- Quality of life issues with endocrine chemoprevention -- Improving quality of life for women at high risk for breast cancer: symptom management without estrogen -- Surgical prevention -- Prophylactic mastectomy and oophorectomy -- Breast reconstruction -- Practical management guidelines.