Abstract
Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis in any vertebrate species. The assay benefits from the practical advantages of bisulfite sequencing while avoiding the cost of whole-genome sequencing. The Diagenode Premium RRBS kit makes this technology widely available and provides high coverage (up to 4 million CpGs in human samples). Multiplexing prior to bisulfite conversion allows processing of 96 samples per experiment, enabling studies of large cohorts.
Cite
CITATION STYLE
Veillard, A. C., Datlinger, P., Laczik, M., Squazzo, S., & Bock, C. (2016). Diagenode® Premium RRBS technology: cost-effective DNA methylation mapping with superior coverage. Nature Methods, 13(2), i–ii. https://doi.org/10.1038/NMETH.F.391
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
