Decision support system for cancer chemotherapy schedules

Abstract

In a chemotherapy scheduling process a chemotherapy is a treatment of cancer using a set of toxic drugs. In the paper we propose a Decision Support System for the anti-cancer medical treatment to improve physicians' decisions about drugs doses selection and scheduling. A hybrid meta-heuristic algorithm has been applied to the problem of bi-criteria optimization allowing to find effective chemotherapy drugs dose scheduling as the minimization of a tumor size at a fixed period of time and maximization of Patient Survival Time. The numerical tests of proposed algorithm gives the possibility of producing a set of alternative treatment scenarios according to the final decision. © 2013 Springer-Verlag Berlin Heidelberg.