Andrology Laboratory Manual

Abstract

A 25 years old woman with Down syndrome (DS) presented at 9 weeks gestational age. She belonged to a very supportive family. She was married to a person with normal karyotype and conceived within 3 months of marriage. Her antenatal period was uneventful, except for mild IUGR and oligohydroamnios 32 weeks onwards. At 38 weeks, she underwent induction of labor. She tolerated labor pains well but because of failure to progress, cesarean section was performed. She delivered a 2 kg male baby, who was phenotypically and genotypically normal. Screening for trisomy 21 should be offered to all women as part of routine antenatal care. This offer should include detailed counseling about the implications and limitations of the test used in the screening program. The available second trimester screening tests are the double, triple and quadruple tests. Children with Down syndrome may benefit from speech therapy, physical therapy and occupational therapy. They may receive special education and assistance in school. Full potential of Down patients can be utilized only with complete support of family and society.