Investigation of the relationship of asprosin and cardiac troponin response with some physiological and biochemical parameters in Anatolian native horse

Abstract

Summary: Asprosin is a recently discovered glucogenic hormone released from starvation-induced white adipose tissue and amongst others it protects against hyperinsulinism associated with metabolic syndrome. The aim of this study was to examine the effect of age, gender and season on metabolic (asprosin) and cardiovascular (cardiac troponin, I (cTnI), CK, CK-MB) function markers and their relationship with some biochemical parameters in Anatolian native horse breed. This study was carried out between February–August 2020. A total of 40 horses was used for this purpose, including 20 mares and 20 stallions in the age range of 1–6, 7–12. Serum asprosin level, for the winter season in stallions and mares aged 1–6 and 7–12 years respectively 8.9, 8.36; 14.08, 13.58ng/ml were as determined. In addition, for the summer season respectively 17.98, 18.68; 22.22, 21.32ng/ml were detected and no difference between the groups (P>0.05). On the other hand, serum cTnI levels for the winter season in stallions and mares aged 1–6 and 7–12 years respectively 0.014, 0.018; 0.016, 0.02ng/ml were as determined. In addition, for the summer season respectively 0.012, 0.016; 0.014, 0.018ng/ml were detected. It was shown that the serum biochemical parameters and levels of cTnI levels in the domestic horse breed the horses belonging to the Anatolian varied depending on age, gender, and season (p < 0.05) but the effect of hormone levels serum asprosin wasn’t found statistically significant (p>0.05).Our results showed that cTnI could be a useful parameter in the examination of the cardiovascular system status of horses.