Abstract
Biomarkers, whether predictive or prognostic of disease, are an essential element of every modern targeted oncology drug development program. Because they can provide information about the mechanism of drug action, carcinogenesis, and patient characteristics specific to both disease and treatment, they offer the opportunity to individualize therapies and to realize potential of personalized medicine. This chapter provides an introduction to biomarkers, their definition and collection, with emphasis on the utility in colon, breast and lung cancers.
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Suenaga, M., Lenz, H. J., & Scherer, S. J. (2016). Overview of oncology biomarkers. In Pharmacokinetics in Drug Development: Problems and Challenges in Oncology, Volume 4 (pp. 29–37). Springer International Publishing. https://doi.org/10.1007/978-3-319-39053-6_2
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