Cu-catalyzed intermolecular oxyalkylation of styrenes under air: Access to diverse iminolactones

Abstract

A practical, simple, and efficient copper-catalyzed highly regioselective oxyalkylation of styrenes and readily available α-bromoacetamides under air is realized. This reaction exhibits a wide range of functional group tolerance in styrenes and α-bromoacetamides to afford iminolactones.