Elionurus tristis Essential Oil: GC-MS Analysis and Antioxidant and Antituberculosis Activities

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Abstract

Essential oil was obtained in a yield 1.1%, w/w, by steam distillation of Elionurus tristis leaves from Madagascar. The chemical composition was analyzed qualitatively and quantitatively by GC-MS and GC-FID, respectively. To the best of our knowledge, this is the first chemical analysis of this essential oil. Seventy-three compounds were identified, corresponding to 94.9% of the total essential oil. The principal compounds were sesquiterpenes and the more represented were β-gurjunene (18.4%), neoclovene (15.8%) and nootkatone (10.4%). Through a comparative study, we observed a large variability between the components of E. tristis essential oil and those from others species of the same genus. Evaluation of the antioxidant (ABTS and DPPH assays) and anti-tuberculosis activities of the essential oil showed weak antioxidant potency but an interesting anti-tuberculosis activity with a MIC of 32 mg/L. This activity prompted us to evaluate individually the major components for the treatment of tuberculosis.

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Yedomon, B. H., Saves, I., Mtimet, N., Raoelison, E. G., Constant, P., Daffé, M., & Bouajila, J. (2017). Elionurus tristis Essential Oil: GC-MS Analysis and Antioxidant and Antituberculosis Activities. Natural Product Communications, 12(4), 615–618. https://doi.org/10.1177/1934578x1701200436

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