Secomycalolide A: A new proteasome inhibitor isolated from a marine sponge of the genus Mycale

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Abstract

A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge of the genus Mycale. They showed proteasome inhibitory activities with IC50 values of 11-45 μg/mL. © 2005 by MDPI.

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Tsukamoto, S., Koimaru, K., & Ohta, T. (2005). Secomycalolide A: A new proteasome inhibitor isolated from a marine sponge of the genus Mycale. Marine Drugs, 3(2), 29–35. https://doi.org/10.3390/md302029

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