The Staphylococcus aureus gamma-hemolysin comprises two polypeptides, whereas the gamma-hemolysin locus (hlg) contains three open reading frames. The hlgA and hlgB genes encode the γ1 and γ2 components, respectively. The HlgB protein (γ2) has 27% residue identity with S. aureus alpha-toxin. Surprisingly, hlgB and hlgC are 98.5 and 99.1% identical to the lukF and lukS genes, respectively, encoding the F and S components of the Panton-Valentine leukocidin.
CITATION STYLE
Cooney, J., Kienle, Z., Foster, T. J., & O’Toole, P. W. (1993). The gamma-hemolysin locus of Staphylococcus aureus comprises three linked genes, two of which are identical to the genes for the F and S components of leukocidin. Infection and Immunity. https://doi.org/10.1128/iai.61.2.768-771.1993
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