Allergic asthma is a complex disease that has been modeled extensively in small rodents. Airway eosinophilia and changes in lung function have been documented using a variety of protocols. However, recent efforts have improved these models by trying to replicate the structural remodeling that occurs in the lung as a consequence of chronic allergen-driven inflammation. This review documents the recent developments in protocols and systems designed to examine pathways leading to allergen-induced airway remodeling. Copyright © 2007 by Current Medicine Group LLC.
CITATION STYLE
Lloyd, C. M. (2007). Building better mouse models of asthma. Current Allergy and Asthma Reports. Current Science Ltd. https://doi.org/10.1007/s11882-007-0077-0
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