Ingredient consistency of commercially available polyphenol and tocopherol nutraceuticals

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Label claims of vitamin E succinate and polyphenolic nutraceuticals are assessed. A validated HPLC method was utilized to assess vitamin E succinate products. Three novel LC/MS methods were used to assess the polyphenols, pterostilbene, phloretin, and myricetin, in dietary supplements. The amount of vitamin E succinate varied from 0-130% of the stated label content with two products containing vitamin E acetate rather than vitamin E succinate. Expected polyphenols were found in 7 of the 8 supplement products. None of the polyphenol supplements contained content within 100-120% of label claims. The present study indicates a lack of uniformity in nutraceutical products. © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.




Remsberg, C. M., Good, R. L., & Davies, N. M. (2010). Ingredient consistency of commercially available polyphenol and tocopherol nutraceuticals. Pharmaceutics, 2(1), 50–60.

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