Aberration-correcting effect of ThinOptX IOL

Abstract

Purpose: To evaluate spherical aberration and visual function after microincision cataract surgery using the ThinOptX rollable intraocular lens. Design: Prospective, comparative, and interventional case series. Methods: Setting: Single-centre institutional practice. This prospective study evaluated 58 patients with cataracts who underwent bimanual microphaco cataract surgery in both eyes. A ThinOptX lens was introduced into one eye and an Alcon Acrysof lens, as a control, into the other. One month after cataract surgery, the corneal, whole-eye, and internal spherical aberration, and contrast sensitivity in both eyes were measured. We also measured the spherical aberration in artificial model eyes bearing Acrysof and ThinOptX lenses. Two-sided paired t-test was used for assessing all data. Results: The root mean square (RMS) for both whole-eye and internal spherical aberrations was smaller in eyes bearing ThinOptX (P=0.03 and P=0.07, respectively). Although there was no statistically significant difference in the RMS for internal spherical aberration between ThinOptX- and Acrysof-bearing eyes, according to the Zernike polynomial expansion, all human and model eyes bearing ThinOptX registered negative internal spherical aberration in Z(4,0) and Z(6,0). On the other hand, all human and model eyes bearing Acrysof registered positive internal spherical aberration in Z(4,0) and Z(6,0). The ThinOptX lens yielded slightly higher contrast sensitivity in all cycles. Conclusion: As the ThinOptX lens is designed for negative spherical aberration, we encountered smaller whole spherical aberrations and higher contrast sensitivity than with the Acrysof lens. The implantation of ThinOptX IOL after microincision cataract surgery yielded good visual function. © 2009 Macmillan Publishers Limited All rights reserved.