Abstract
Gamma-butyrolactones (GBLs) are signalling molecules that control antibiotic production in Streptomyces bacteria. The genetically engineered strain S. coelicolor M1152 was found to overproduce GBLs SCB1-3 as well as five novel GBLs named SCB4-8. Incorporation experiments using isotopically-labelled precursors confirmed the chemical structures of SCB1-3 and established those of SCB4-8.
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CITATION STYLE
APA
Sidda, J. D., Poon, V., Song, L., Wang, W., Yang, K., & Corre, C. (2016). Overproduction and identification of butyrolactones SCB1-8 in the antibiotic production superhost: Streptomyces M1152. Organic and Biomolecular Chemistry, 14(27), 6390–6393. https://doi.org/10.1039/c6ob00840b
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