Institutional ethics committee regulations and current updates in India

Abstract

Aim: The aim of the review is to provide current updates on regulations for ethics committees and researchers in India. Background: Ethical dilemmas in research since time immemorial have been a major concern for researchers worldwide. The question "what makes clinical research ethical" is significant and difficult to answer as multiple factors are involved. Review results: The research involving human participants in clinical trials should follow the required rules, regulations, and guidelines in one's own country. It is a dynamic process, and updates have to be learned by researcher and committee members. The review highlights the ethical regulation from the Drug Controller General of India, Clinical Trial Registry of India, and Indian Council of Medical Research guidelines. Conclusion: In this article, the updates on Indian scenario of the Ethical Committee and guidelines are compiled. Clinical significance: The review comes handy for clinical researchers and ethics committee members in academic institutions to check on the current updates and keep abreast with the knowledge on regulations of ethics in India.