ReGenX AAV Vector Technology: a tool for in vivo screening

Abstract

Transgenic and knockout mice have been used to create disease models and understand gene function. However, such mice are complex to create, breeding colonies must be established, and some models are not viable. Somatic gene transfer with vectors such as adeno-associated virus (AAV) can overcome these limitations. ReGenX’s AAV Vector Technology gives extremely efficient and stable gene expression in neonatal and adult animals, and can be used to create disease models and to study gene function and target validation.