use of amniotic membrane for wound healing in burn injuries

Abstract

Background: Burn injuries are associated with significant mortality and morbidity around the world. The care of burn wounds requires a great amount of medical resources therefore it is important to find a wound dressing that accelerates wound healing and is readily available. Objectives: This review article will provide an overview of the literature and background of the usage of amniotic membranes in burn patients. We will also discuss its properties of preventing infections, relieving pain, how it promotes and accelerates wound healing. Discussion: Human amniotic membrane is now used around the world as a relatively cheap temporary dressing for burn wounds. It has been shown to promote wound healing, create a moist environment, reduce pain intensity, reduce scar formation, prevent water and electrolyte disturbances and also reduce the risk of infections. Research has also shown that it contains antimicrobial properties that could be of great benefit in burn patients and is compatible to use in developing countries because it is readily available, easy to obtain and sterilize, able to cover wounds of large size, protects the wound from excessive water and electrolyte loss, reduces pain intensity, requires fewer dressing changes and is also more cost effective than conventional dressings. Conclusion: Amniotic membrane is a biological dressing that can be useful in the treatment of burn wounds. Further research should be conducted to investigate and understand the mechanisms of amniotic membrane for burn and wound care.