Bioactivities of triterpenes and a sterol from Syzygium samarangense

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Abstract

Cycloartenyl stearate (1a), lupenyl stearate (1b), sitosteryl stearate (1c), and 24-methylenecycloartanyl stearate (1d) (sample 1) from the air-dried leaves of Syzygium samarangense exhibited potent analgesic and anti-infl ammatory activities at effective doses of 6.25 mg/kg body weight and 12.5 mg/kg body weight, respectively. Sample 1 also exhibited negligible toxicity on zebrafi sh embryonic tissues. There were incidences of mortality upon direct exposure of sample 1 to dechorionated embryos, but higher mortality and aberration were observed during intact chorion treatment. © 2011 Verlag der Zeitschrift für Naturforschung, Tübingen.

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Raga, D. D., Cheng, C. L. C., Lee, K. C. I. C., Olaziman, W. Z. P., de Guzman, V. J. A., Shen, C. C., … Ragasa, C. Y. (2011). Bioactivities of triterpenes and a sterol from Syzygium samarangense. Zeitschrift Fur Naturforschung - Section C Journal of Biosciences, 66 C(5–6), 235–244. https://doi.org/10.1515/znc-2011-5-606

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