Processing Affymetrix Expression Data

  • Gentleman R
  • Huber W
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Abstract

In this chapter we do an analysis of Affymetrix gene expression data. We begin with the CEL files that contain the raw microar- ray readings, discuss how to do quality assessment, and proceed to normalization and the estimation of expression values. Finally, we determine differentially expressed genes.

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Gentleman, R., & Huber, W. (2008). Processing Affymetrix Expression Data. In Bioconductor Case Studies (pp. 25–45). Springer New York. https://doi.org/10.1007/978-0-387-77240-0_3

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