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Book Chapter

MLH1

Springer New York, (2017), 893-902
DOI: 10.1007/978-1-4419-0717-2_8
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Abstract

MLH1 along with other mismatch repair (MMR) genes play a critical role in postreplicative MMR during DNA replication. Hereditary nonpolyposis colon cancer (HNPCC) is associated with mutations in MLH1 and other MMR genes. Mutations in MLH1 are associated with the microsatellite instability (MSI) seen in colon cancers.

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Kinsella, T., & Leonard, K. L. (2017). MLH1. In Cancer Therapeutic Targets (Vol. 2–2, pp. 893–902). Springer New York. https://doi.org/10.1007/978-1-4419-0717-2_8

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