Saponins from Vietnamese Ginseng, Panax vietnamensis Ha et Grushv. Collected in Central Vietnam. III

Abstract

Five new dammarane saponins derived from four new aglycones were isolated from the rhizomes and roots of Panax vietnamensis Ha et Grushv. On the basis of physicochemical and spectral evidence, the structures of these compounds were established as 6-O-β-D-glucopyranosyl 20(S),25-epoxydammarane-3β,6α,12β,24α-tetrol (1), 6-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranosyl 20(S),25-epoxydammarane-3β,6α,12β,24α-tetrol (2), 6-o-β-d-glucopyranosyl dammarane-3β,6α,12β,20(S),24ξ,25-hexol (5), 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyrano-syl]-20-O-β-D-glucopyranosyl dammarane-3β,12β,20(S),24ξ,25-pentol (8) and 6-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranosyl 20(S),24(S)-epoxydammarane-3β,6α,12β,25ξ,26-pentol (10). The trivial names, vina-ginsenoside-R10, -R11, -R12, -R13 and -R14, respectively, were assigned to the new saponins. © 1994, The Pharmaceutical Society of Japan. All rights reserved.