The Pancreas: Biology, Pathobiology and Disease

Abstract

2nd ed. Revised edition of: The Exocrine pancreas / Vay Liang W. Go [and others]. c1986. Anatomy of the pancreas -- Fine structure of the human exocrine pancreas -- Differentiation and development of the pancreas in animals -- Prenatal and postnatal development of the human exocrine pancreas -- Replication and regeneration of the pancreas -- Transgenic analysis of pancreatic function and development -- Regulation of pancreatic gene expression in response to hormones and nutritional substrates -- Cellular compartmentation, protein processing and secretion in the exocrine pancreas -- Receptors for secretagogues on pancreatic acinar cells -- Stimulus-secretion coupling in pancreatic acinar cells -- Electrophysiology of acinar cells -- Pancreatic secretory enzymes -- Lithostathine -- Use of two-dimensional gel electrophoresis and high-performance liquid chromatography for the analysis of pancreatic juice -- Human exocrine pancreatic enzyme secretion -- Pancreatic duct cell secretion: control and mechanisms of transport -- Pancreatic mucins -- Extracellular matrix as a regulator of epithelial polarity, cell growth and tissue pattern -- Neural regulation of pancreatic exocrine function. (cont) Hormonal control of pancreatic exocrine secretion -- Neurohormonal control of pancreatic enzyme secretion in animals -- Interdependence of nutrition and exocrine pancreatic function -- Luminal digestion of fats -- Experimental acute pancreatitis: studies of the early events that lead to cell injury -- Cerulein-induced pancreatitis -- Permeability characteristics of the main pancreatic duct in cats: models of acute and chronic pancreatitis -- Experimental models of exocrine pancreatic tumors -- Cell lines of the human and rodent exocrine pancreas -- Pancreatitis definitions and classification -- Etiology and pathophysiology of acute pancreatitis -- Medical management of acute pancreatitis and complications -- Diagnosis of acute pancreatitis -- Acute pancreatitis: surgical management -- Pancreatic abscess -- Chronic pancreatitis -- Surgical treatment of chronic pancreatitis -- Diagnosis and management of pancreatic pseudocysts, pancreatic ascites and pancreatic fistulas -- Normal function of the endocrine pancreas -- Enteroinsular axis -- Insulin-acinar relationship. (cont) Microvasculature of the pancreas, with emphasis on that of the Islets of Langerhans: anatomy and functional implications -- Endocrine changes in pancreatic insufficiency -- Pancreas and islet transplantation -- Epidemiology and etiology of pancreatic cancer -- Fine structure of human pancreatic adenocarcinoma -- Pathology of nonendocrine pancreatic tumors -- Exocrine tumors of the pancreas -- Surgical management of exocrine pancreatic cancer -- Gastrinoma -- Insulinoma -- Miscellaneous tumors of the pancreas -- Surgery for endocrine tumors of the pancreas -- Congenital abnormalities of the exocrine pancreas -- Pancreas in cystic fibrosis -- Hereditary diseases of the pancreas -- Hereditary pancreatitis -- Imaging of the pancreas.