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Environmental Effects of Lactate on High-Five™ Insect Cell Metabolism

  • Drugmand J
  • Schneider Y
  • Agathos S
Springer-Verlag, (2005), 91-94
DOI: 10.1007/1-4020-3103-3_14
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Abstract

In batch suspension culture of High-Five (TM) insect cells without oxygen limitation, we observed that during the growth phase the presence of exogenous lactate in the medium seems to increase its accumulation by the cells and inhibits cell growth. At the end of culture, after glucose exhaustion from the medium, High-Five (TM) cells are able to use the produced lactate as a carbon source.

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Drugmand, J.-C., Schneider, Y.-J., & Agathos, S. N. (2005). Environmental Effects of Lactate on High-FiveTM Insect Cell Metabolism. In Animal Cell Technology Meets Genomics (pp. 91–94). Springer-Verlag. https://doi.org/10.1007/1-4020-3103-3_14

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