Abstract
Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and HRMS. The application of this system to identify, purify and elucidate all the structures is described.
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Thomasi, S. S., Granato, A. C., Romano, L. H., Dhooghe, L., Do Nascimento, E. S. P., Badino, A. C., … Venâncio, T. (2014). Unusual 2(1H)-pyrazinones isolated from a culture of a Brazilian marine-derived Streptomyces sp. Natural Product Communications, 9(9), 1275–1278. https://doi.org/10.1177/1934578x1400900913
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