We report on theoretical and experimental considerations on bacteria capturing and enrichment via magnetic separation enabling integrated diagnosis and treatment of blood stream infections. We show optimization of carrier-pathogen interactions based on a mathematical model followed by an experimental proof-of-concept study along with investigations on the process safety.
Lattuada, M., Ren, Q., Zuber, F., Galli, M., Bohmer, N., Matter, M. T., … Herrmann, I. K. (2016). Theranostic body fluid cleansing: Rationally designed magnetic particles enable capturing and detection of bacterial pathogens. Journal of Materials Chemistry B, 4(44), 7080–7086. https://doi.org/10.1039/c6tb01272h
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