Lymphoma in other diseases

Abstract

When lymphomas occur in association with other diseases, usually the underlying disease or its treatment produces immunodysregulation [1]. In most cases, this immune dysfunction takes the form of immunodeficiency, which can result from either inherited or acquired defects [2]. Such acquired immunodeficiencies may be associated with infectious diseases, most commonly viral infections [3-6], transplants with intentional iatrogenic immunosuppression [7, 8], and chemical environmental agents [9, 10]. However, in the autoimmune disorders, a different set of mechanisms are operative, since affected individuals demonstrate hyperactivity of the immune system.