Histopathological Spectrum of Nephrectomy Specimens: Single Center Experience

Abstract

Background: The kidneys are by and large a very resilient organ. The renal parenchyma though subjected to repeated trauma/insults of the noxious environment, they are the last to respond. The kidneys are affected by various disease processes some resulting in permanent damage leading to surgical removal of the organ i.e.nephrectomy. Indications for nephrectomy are varied including irreversible damage by chronic infections, obstructive causes including strictures & calculus disease, vesicouretric reflex, congenital dysplasia, nephrosclerosis, cystic disease, dysplasia'sand also severe traumatic injury, non-corrective renal artery disease leading to renovascular hypertension.Common indication for nephrectomy would be obstructive nephropathy, hydronephrosis and chronic pyelonephritis according to studies. Nephrectomy procedure may show geographic variations with variable urological causes. Indications for nephrectomy may show geographic variations with differenturologic causes in different countries worldwide.