Diagnosis of acute cardiac ischemia depends on characteristic shifts of the ST segment. The transmural extent of the ischemic region and the temporal stage of ischemia have an impact on these changes. In this work, computer simulations of realistic ventricles with different transmural extent of the ischemic region were carried out. Furthermore, three stages within the first half hour after the occlusion of the distal left anterior descending coronary artery were regarded. The transmembrane voltage distributions and the corresponding body surface ECGs were calculated. It was observed how the electrophysiological properties worsen in the course of ischemia, so that almost no excitation was initiated in the central ischemic zone 30 minutes after the occlusion. In addition to these temporal effects, also the transmural extent of the ischemic region had an impact on the direction and intensity of the ST segment shift. © 2011 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Wilhelms, M., Dössel, O., & Seemann, G. (2011). Comparing simulated electrocardiograms of different stages of acute cardiac ischemia. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 6666 LNCS, pp. 11–19). https://doi.org/10.1007/978-3-642-21028-0_2
Mendeley helps you to discover research relevant for your work.