Recovery and relapse from severe acute malnutrition after treatment: A prospective, observational cohort trial in Pakistan

7Citations
Citations of this article
89Readers
Mendeley users who have this article in their library.

Abstract

Objective Millions of children suffer from severe acute malnutrition (SAM) in low-and middle-income countries. Much is known about the effectiveness of community treatment programmes (CMAM) but little is known about post-discharge outcomes after successful treatment. The present study aimed to evaluate post-discharge outcomes of children cured of SAM.Design Prospective, observational cohort study. Children with SAM who were discharged as cured were followed monthly for 6 months or until they experienced relapse to SAM. 'Cure' was defined as a child achieving a mid-upper arm circumference (MUAC) of ≥115 mm with ≥15 % weight gain after loss of oedema. Relapse was defined as a child with MUAC<115 mm and/or oedema at any monthly visit.Setting Save the Children CMAM programme in Swabi, Pakistan, from January 2012 to December 2014.Subjects Children aged 6-59 months (n 117) discharged as cured from the CMAM programme were eligible for the study and followed for 6 months.Results One hundred children (92·6 %) remained free of SAM, eight (7·4 %) relapsed to SAM, nine (8·3 %) were lost to follow-up and none died. Most relapses occurred within 3 months of discharge (mean time to relapse 73·4 (sd 36·2) d). At enrolment, 90 % had moderate acute malnutrition (MAM) and 10 % were not malnourished. By the end of 6 months, 35 % persisted with MAM and the remaining were not malnourished.Conclusions In rural Pakistan, fewer than 10 % of children cured of SAM relapsed. The first 3 months is the most vulnerable time.

References Powered by Scopus

Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support

35361Citations
N/AReaders
Get full text

Comparison of home-based therapy with ready-to-use therapeutic food with standard therapy in the treatment of malnourished Malawian children: A controlled, clinical effectiveness trial

212Citations
N/AReaders
Get full text

Home based therapy for severe malnutrition with ready-to-use food

171Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Incidence of severe acute malnutrition after treatment: A prospective matched cohort study in Sokoto, Nigeria

20Citations
N/AReaders
Get full text

Time to readmission and associated factors after post treatment discharge of severe acute malnourished under-five children in Pawe General Hospital

4Citations
N/AReaders
Get full text

Relapse of acute malnutrition and associated factors after discharge from nutrition stabilization centers among children in Eastern Ethiopia

1Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Dale, N. M., Salim, L., Lenters, L., Sadruddin, S., Myatt, M., & Zlotkin, S. H. (2018). Recovery and relapse from severe acute malnutrition after treatment: A prospective, observational cohort trial in Pakistan. Public Health Nutrition, 21(12), 2193–2199. https://doi.org/10.1017/S1368980018000745

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 22

69%

Researcher 5

16%

Lecturer / Post doc 3

9%

Professor / Associate Prof. 2

6%

Readers' Discipline

Tooltip

Nursing and Health Professions 14

45%

Medicine and Dentistry 9

29%

Agricultural and Biological Sciences 6

19%

Social Sciences 2

6%

Save time finding and organizing research with Mendeley

Sign up for free