Abstract
Useful diversity: Quantification of modified tRNA nucleobases in different murine and porcine tissues reveals a tissue-specific overall modification content. The modification content correlates with rates of protein synthesis vitro, suggesting a direct link between tRNA modification levels and tissue-specific translational efficiency. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Brandmayr, C., Wagner, M., Brückl, T., Globisch, D., Pearson, D., Kneuttinger, A. C., … Carell, T. (2012). Isotope-based analysis of modified trna nucleosides correlates modification density with translational efficiency. Angewandte Chemie - International Edition, 51(44), 11162–11165. https://doi.org/10.1002/anie.201203769
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