This study demonstrates that the human immunodeficiency virus (HIV) binding C-type lectin DC-SIGN is coexpressed with CD4 and CCR5 on dendritic cells/macrophages in human foreskin. It is hypothesised that DC-SIGN may contribute to the sexual transmission of HIV in the foreskin, by enabling infection of permissive cells in cis and/or in trans.
CITATION STYLE
Soilleux, E. J., & Coleman, N. (2004). Expression of DC-SIGN in human foreskin may facilitate sexual transmission of HIV. Journal of Clinical Pathology, 57(1), 77–78. https://doi.org/10.1136/jcp.57.1.77
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