Multifunctional Biosensor Logic Gates Based on Graphene Oxide

Abstract

In this paper, a biological sensing model based on graphene oxide is proposed. A YES gate and a AND gate are constructed by using the ability of graphene oxide to adsorb single strand and quench fluorescence. The biosensor we designed can be used not only as a logical element, but also to detect a specific target DNA. Then, taking YES gate as an example, orthogonal experiments, condition optimization and target selective detection are carried out to demonstrate the practical significance of the sensing model designed. In subsequent experiments, we will design more complex logic components on this basis and try to apply them to practice.