Magnetically targeted drug transport and fixation

Abstract

This paper presents a mathematical model and numerical simulation results on transport and targeting of a medical substance carried by magnetic nanoparticles through a high gradient magnetic field. In our study we use simpler yet consistent models for the hemodynamic flow, and more complex, realistic computational domains based on medical images for the iliac arterial branching. The biocompatible drug carrier is injected in the blood. An optimized array of permanent magnets generates the targeting magnetic field, in the process of medication delivery in the region of therapeutic concern.