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The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis

OncoImmunology (2013) 2(4)
DOI: 10.4161/onci.23566
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Abstract

A replication-incompetent hemagglutinating virus of Japan (HVJ) envelope (HVJ-E) induces apoptosis selectively in cancer cells. Fragments of the viral RNA genome transported by HVJ-E are recognized by retinoic acid-inducible gene I (RIG-I) and mitochondrial antiviral signaling (MAVS). Specific pro-apoptotic factor are selectively upregulated in cancer cells downstream of the RIG-I/MAVS pathway. © 2013 Landes Bioscience.

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Kaneda, Y. (2013). The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis. OncoImmunology, 2(4). https://doi.org/10.4161/onci.23566

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