Mechanistic Insights for Optimizing PSMA Radioligand Therapy

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Abstract

PSMA radioligand therapy is a promising new class of therapy for prostate cancer. Heterogeneity of PSMA expression is an important factor explaining variability in clinical results. The ability to visualize the target with theranostics provides unique mechanistic insights. Potential clinically applicable strategies to improve patient selection and optimize therapeutic efficacy are discussed.

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Ravi Kumar, A. S., & Hofman, M. S. (2020). Mechanistic Insights for Optimizing PSMA Radioligand Therapy. Clinical Cancer Research, 26(12), 2774–2776. https://doi.org/10.1158/1078-0432.CCR-20-0209

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