Engrailed2 and Cerebellar Development in the Pathogenesis of Autism Spectrum Disorders

Abstract

Creative thinking and collaborative scientific research have advanced our understanding of autism, and we are now beginning to synthesize the data into evidence and theories. Our lack of knowledge about the causes and patho- genesis of autism has been associated with widely divergent approaches to diagnosis and management, most of which have not been subjected to rigorous scientific scrutiny. The consequence for affected families is that while they recognize the importance of early intervention for their children, they are often left with indecision and confusion as to how to proceed. This book presents current theories about autism and the evidence that supports them. The goal is to show how the scientific method is revealing the biological bases of this spectrum of disorders, thereby leading the way to their treatment and prevention using evidence-based medicine. Quotations