Coronally advanced flap surgery with enamel matrix derivative in the treatment of gingival recession: A systematic review

Abstract

Objective: Based on a review of the literature, we evaluated the clinical effect of the combination of enaml matrix derivative proteins (EMDP) and coronally advanced flap (CAF) surgery in the treatment of gingival recession (GR). Methods: Information was retrieved from the electronic databases PubMed, Lilacs, Scielo, Medline and the Cochrane Library. Controlled, randomized clinical studies of intervention in humans published in English or Spanish between 2000 and 2013 were eligible. Results: The initial sample consisted of 171 publications. Of these, eight were selected which compared CAF+EMDP (study) with CAF alone (control) in the treatment of GR. Invariably, RH decreased in both the study group and the control group. Likewise, GR width and probing depth decreased and the clinical attachment level increased in both groups, but results were significantly better in the study group. Conclusion: Despite the absence of an overall significant difference between treatment with CAF + EMDP and CAF alone, the addition of EMDP appears to increase the likelihood of achieving complete root coverage and clinically and aesthetically satisfactory results.