Despite the recent substantial technological developments in X-ray crystallography, solving and refining structures at low resolutions remain substantial challenges. Many macromolecular crystals, especially those of large molecules or multicomponent assemblies, diffract X-rays to resolutions that are worse than 3.5Å. This report summarizes several recent advances aiding low resolution crystallographic work. © 2010 Faculty of 1000 Ltd.
Dyda, F. (2010, November 11). Developments in low-resolution biological X-ray crystallography. F1000 Biology Reports. https://doi.org/10.3410/B2-80