Synapse: A Clinical Trial Examining the Impact of Actively Engaging the Aging Mind

Abstract

A fundamental challenge and responsibility for modern science is to progress toward understanding neuroprotective factors that will support and optimize cognitive aging. The present chapter describes the scientifically driven efforts of our research group to this end. We do this in three ways beginning with a review of the latest findings regarding the neurocognitive declines that are part of the normal aging process. Next, we present the Scaffolding Theory of Aging and Cognition (STAC; Annu Rev Psychol 60:173-196, 2009), which describes a model for how the brain adapts to the neural deterioration that occurs as a natural part of the aging process. Finally, we introduce a program of research designed using the tenets of the STAC model to investigate how engaging in cognitively and socially stimulating activities may promote the neurocognitive health of seniors long term.