Characterization at 25°C of Sodium Hyaluronate in Aqueous Solutions Obtained by Transport Techniques

Abstract

Mutual diffusion coefficients, D, were determined for aqueous solutions of sodium hyaluronate (NaHy) at 25°C and concentrations ranging from 0.00 to 1.00 g·dm -3 using the Taylor dispersion technique. From these experimental data, it was possible to estimate some parameters, such as the hydrodynamic radius R h, and the diffusion coefficient at infinitesimal concentration, D 0, of hyaluronate ion, permitting us to have a better understanding of the structure of these systems of sodium hyaluronate in aqueous solutions. The additional viscosity measurements were done and Huggins constant, k H, and limiting viscosity number, [η], were computed for interaction NaHy/water and NaHy/NaHy determination.