Intracoronary thrombogenicity in patients with vasospastic angina: An observation using coronary angioscopy

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Abstract

Background: Despite significant interest in intracoronary thrombi in patients with va-sospastic angina (VSA), the phenomenon remains unclarified. Therefore, we investigated a possible relationship using coronary angioscopy (CAS) in VSA patients. Methods: Sixty patients with VSA, for whom we could assess the spastic segment using CAS, were retrospectively studied. An intracoronary thrombus on CAS was a white thrombus and an erosion-like red thrombus. We verified the clinical characteristics and lesional characteristics as they determined the risk of intracoronary thrombus formation. Results: There were 18 (30%) patients with intracoronary thrombi. More of the patients with intracoronary thrombi were male, current smokers and had severe concomitant symptoms; however, no statistically significant difference was observed upon logistic regression analysis. There were 18 (26%) coronary arteries with intracoronary thrombi out of 70 coronary arteries recognised in the spastic segments. Furthermore, atherosclerotic changes and segmental spasms were significant factors responsible for such lesions. Conclusion: Intracoronary thrombi occurred in 30% of VSA patients and much attention should be paid to the intracoronary thrombogenicity of VSA patients.

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Teragawa, H., Orita, Y., Oshita, C., & Uchimura, Y. (2021). Intracoronary thrombogenicity in patients with vasospastic angina: An observation using coronary angioscopy. Diagnostics, 11(9). https://doi.org/10.3390/diagnostics11091632

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