Background: Granular cell tumor (GCT) of the thyroid is a rare benign tumor of Schwann cell origin with a favorable prognosis and only 10 cases have been reported so far in scientific literature. The present case study describes the first case of recurrent thyroid GCT. Case presentation: Our case describes a 20-year-old woman who had undergone lobectomy for GCT of the thyroid 4 years ago. Hematoxylin-eosin (HE) staining revealed that the lesion was composed of epithelioid cells with an abundance of eosinophilic granular cytoplasm. Immunohistochemical analysis showed that tumor cells tested positive for S-100 protein and negative for desmin. Both histological and immunohistochemical analyses supported the diagnosis of recurrent GCT of the thyroid. Conclusions: Our case suggested that a tumor-free margin excision and post-operative follow-up are necessary for the treatment of GCT of the thyroid.
CITATION STYLE
He, Y. Q., Lu, H. Z., Li, D. Z., Chen, M. Q., Wang, K., Xu, Z. G., & Liu, S. Y. (2020, July 14). Recurrent granular cell tumor of the thyroid: A case report and literature review. BMC Surgery. BioMed Central. https://doi.org/10.1186/s12893-020-00814-8
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