DPPH scavenging property of bioactives from soft corals origin palu bay, Central Sulawesi, Indonesia

Abstract

Antioxidants is a substance widely explored and sought after, due to the increase of free radicals in the human body, is very closely linked to the human degenerative disease. Soft corals are also reported to produce compounds that show antioxidant activity. This research aimed to examine the antioxidant and profile bioactive of six soft corals species from three genera Sinularia, Sarcophyton and Nephthea origin Palu Bay, Central Sulawesi. The antioxidant activity was measured by the DPPH radical scavenging method. Profile bioactive were identified using GC-MS spectra analysis. The results of IC50 analysis showed the crudes of soft corals belonging to the very strong antioxidant activity. Sinularia sp. (SCA) has the highest (IC50 = 10.708 ± 0.374 μg/mL). The GC-MS analysis showed 2-Dodecen-1-yl (-) succinic anhydrid; Hexadecanoic acid, methyl ester; Bacchotricuneatin c; L - (+) - Ascorbic acid 2,6-dihexadecanoate; 14 (β) -Pregnane; Octacosane; Heptacosane; and Tetrapentacontane, 1,54-dibromoare common compounds that have the potential as antioxidants. This study provides on the potential soft corals origin Palu Bay, Central Sulawesi as a source of antioxidant. This study also shows the compounds in soft coral according to GC-MS.This is a new report of antioxidant substances from Nephthea sp. origin of Indonesian oceans.