Medical and therapeutic aspects of hyperhomocysteinemia

Abstract

Elevated homocysteine levels increase the chance of risk of developing Coronary artery disease, myocardial infarctions and strokes [1, 2]. In addition, the impact of elevated homocysteine levels on neuroexcitation and vascular function is said to catalyze the progression of types of dementia disorders [3, 4]. Furthermore, patients with severely elevated homocysteine levels are characterized with mental retardation/dementia-type disorders as well as the narrowing of arterial vessels through atherothrombosis [5]. In addition, adult patients with hyper-elevated levels of homocysteine frequently showcased premature diabetic retinopathy [6, 7] and osteoporosis [8].