Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: A real-world study

12Citations
Citations of this article
24Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Background: In an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA). However, the impact of tourniquet use on transfusion rate and postoperative length of stay (PLOS) in TKA remains controversial. Therefore, we carried out a study to investigate the effect of tourniquet application in routine primary TKA on transfusion rate and PLOS. Methods: We analyzed data from 6325 patients who underwent primary unilateral TKA and divided them into two groups according to whether a tourniquet was applied during the procedure, and a tourniquet was used in 4902 and not used in 1423. The information for transfusion and PLOS was extracted from patients' electronic health records, and the data were analyzed with logistic and linear regression analyses. Results: Following TKA, the transfusion rate and PLOS were 14.52% and 7.72 ± 3.54 days, respectively, in the tourniquet group, and 6.47% and 6.44 ± 3.48 days, respectively, in the no-tourniquet group. After adjusting for the different related variables, tourniquet use was significantly correlated with a higher transfusion rate (risk ratio = 1.888, 95% confidence interval (CI) 1.449-2.461, P < 0.001) and a longer PLOS (partial regression coefficient (B) = 0.923, 95%CI 0.690-1.156, P < 0.001). Conclusions: Our findings suggested that tourniquet use in routine primary TKA was related to a higher transfusion rate and a longer PLOS. The impact of tourniquet use on transfusion rate and PLOS should be taken into account in clinical practice.

References Powered by Scopus

Multimodal strategies to improve surgical outcome

1484Citations
N/AReaders
Get full text

Tranexamic Acid: A review of its use in the treatment of hyperfibrinolysis

512Citations
N/AReaders
Get full text

Controlled hypotension: A guide to drug choice

301Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Tourniquet use in total knee arthroplasty and the risk of infection: a meta-analysis of randomised controlled trials

12Citations
N/AReaders
Get full text

Tourniquet use in primary total knee arthroplasty is associated with a hypercoagulable status: a prospective thromboelastography trial

10Citations
N/AReaders
Get full text

Effect of tourniquet use on blood loss, pain, functional recovery, and complications in robot-assisted total knee arthroplasty: a prospective, double-blinded, randomized controlled trial

9Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Xu, H., Yang, J., Xie, J., Huang, Z., Huang, Q., Cao, G., & Pei, F. (2020). Tourniquet use in routine primary total knee arthroplasty is associated with a higher transfusion rate and longer postoperative length of stay: A real-world study. BMC Musculoskeletal Disorders, 21(1). https://doi.org/10.1186/s12891-020-03623-5

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 6

86%

Researcher 1

14%

Readers' Discipline

Tooltip

Medicine and Dentistry 10

63%

Nursing and Health Professions 5

31%

Biochemistry, Genetics and Molecular Bi... 1

6%

Save time finding and organizing research with Mendeley

Sign up for free