• A TCP curve is created by plotting some measure of tumor control probability against the total dose. • This may be done with clinical or experimental data, or with theoretical models. • Even when plotting clinical data, a theoretical model must be used to model the response of tumor cells to radiation therapy. ° See Chapt. 21 for details of single-target and linear-quadratic models. • A TCP curve is characterized by a sigmoid shape, in which there is little dose-response at very low or very high doses, and a steep dose-response at intermediate doses. D.S. Chang et al.,
CITATION STYLE
Chang, D. S., Lasley, F. D., Das, I. J., Mendonca, M. S., & Dynlacht, J. R. (2014). Therapeutic Ratio. In Basic Radiotherapy Physics and Biology (pp. 277–282). Springer International Publishing. https://doi.org/10.1007/978-3-319-06841-1_27
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