A new diacylated labdane diterpenoid from Andrographis wightiana

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Abstract

A new acylated labdane diterpenoid, 14-deoxy-3,19-diacetyl-11,12- didehydroandrographolide (1), together with three known labdane diterpenoids, wightionolide (2), andrographolide (3) and neoandrographolide (4), and three known flavones, echioidinin (5), skullcapflavone I 2'-methyl ether (6) and echioidin (7), were isolated from the whole plant of Andrographis wightiana. The structure of compound 1 was elucidated by 1D and extensive 2D-NMR spectral studies.

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Sudhana, J. M., Munikishor, R., Reddy, M. V., Gunasekar, D., Blond, A., & Bodo, B. (2011). A new diacylated labdane diterpenoid from Andrographis wightiana. Natural Product Communications, 6(11), 1569–1572. https://doi.org/10.1177/1934578x1100601102

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