Large-scale simulation for HIFU treatment to brain

Abstract

The focused ultrasound wave attracts attention in the medical field invarious applications such as High Intensity Focused Ultrasound (HIFU).Amount Of Sound energy is generated by focused ultrasound in the body ofnarrow area. Present HIFU treatment cannot be applied to the partsurrounded by bones, such as brain, because focal point is changed byrefraction and reflection of ultrasound. In this research transskullultrasound propagation is analyzed by finite difference method for HIFUtreatment to brain. Assumption of isentropy and small disturbance ofEuler equation gives the governing equation. The density and speed ofsound of each medium are given at the center of Cartesian grid cells soas to model arbitrary human body from Computerized Tomography scanimages. Transskull focused ultrasound is simulated to examine the effectof the inhomogeneity of the skull and ultrasound frequency to the focus.